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Supply Notification: Clonidine 25mcg tablets – Update
Update (17/01/2020): resupply date now expected mid/end February 2020 First published 20th December 2019 Department of Health and Social Care (DHSC) has issued a medicine supply notification for Clonidine 25mcg tablets. Limited supplies of Clonidine 25mcg tablets will be available until at least mid-January 2020 due to manufacturing issues. The DHSC Medicine Supply Team provide...

Shortage Notice: Synphase (Ethinylestradiol and Norethisterone) tablets – Update
Update (17/01/2020): resupply date now expected end January 2020 First published 15th November 2019 Issued: 14 November 2019 The Department of Health and Social Care (DHSC) have advised that Synphase tablets are out of stock until 20 December 2019. Other brands of phasic oral contraceptive tablets remain available during this period. Action required:  For patients...

Shortage Notice – Disopyramide 150mg capsules – Update
Update (17/01/2020) resupply date now March 2020 First published 15th November 2019 MSN/2019/007U, update to SDA/2019/002 Date issued 14th November DHSC have advised that Mylan, the sole supplier of disopyramide 150mg capsules, has had a delay to their resupply date. Mylan will be out of stock of Disopyramide 150mg capsules to approximately 13th December 2019....

Shortage Notice: Salofalk (mesalazine) suppositories (500mg and 1g) – Update
Update (17/01/2020): resupply date now expected mid April 2020 for the 500mg suppositories, no date confirmed for the 1g suppositories. First published 24th October 2019 Dr Falk the sole supplier of the 500mg mesalazine suppository (Salofalk suppositories 500mg) has announced that they expect to be out of stock of this line until mid-December 2019. The...

Shortage Notice: Seroxat (paroxetine) 20mg/10ml oral solution – Update
Update (17/01/2020): resupply date now expected end February 2020 First published 25th October 2019 The Department of Health and Social Care (DHSC) have advised that paroxetine 20mg/10ml oral solution will be out of stock until January 2020 due to manufacturing delays. Paroxetine tablets remain available from various suppliers. Action required:  For patients who do not...

Shortage Notice: Mianserin 10mg and 30mg tablets – Update
Update (17/01/2020): resupply date now expected June 2020 First published 16th September 2019 Mylan,  the sole manufacturers of Mianserin 10mg and 30mg tablets, are currently experiencing temporary supply disruptions. Mylan,  the sole manufacturers of Mianserin 10mg and 30mg tablets have advised a resupply date of end of 2019 Supplies are available from specialist importers on...

Sayana Press (medroxyprogesterone acetate) injection supply issue – Update
Update (17/01/2020): resupply date now expected Q1 2020 First published 23rd August 2019 Pfizer, the sole supplier of Sayana Press (medroxyprogesterone acetate 104mg) in the UK,  have informed the Department of Health and Social Care that due to  manufacturing delays, Sayana Press will be out of stock until at least the end of 2019. Depo-Provera (medroxyprogesterone...

Supply Disruption: Azathioprine 25mg tablets
Department of Health and Social Care (DHSC) has issued a supply disruption notification for Azathioprine 25mg tablets. All suppliers of Azathioprine 25mg tablets are out of stock until the w/c 27th January 2020. The DHSC Medicine Supply Team provide a monthly update on potential supply issues affecting both primary and secondary care. This update is...

Service case study: Pharmacy4Mums2B pilot provides ‘excellent’ service
Pharmacy4Mums2B (P4M2B) is a community pharmacy service in North West London which provides support to women throughout pregnancy and for the first three years of their child’s life. The pilot was developed in collaboration between the Department of Paediatrics at Northwick Park Hospital LNWUH Trust, the Academic Department of Paediatrics at Imperial College London, and...

Service case study: AF pilot targets patients in deprived areas
A pilot scheme has recently launched in Knowsley, which aims to optimise the role of community pharmacy in supporting primary care in the detection and monitoring of patients with atrial fibrillation (AF).  Background Ongoing public health research has shown that people with cardiovascular disease living in more deprived areas are twice more likely to die...

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Ibrance given NICE green light in breast cancer
The recommendation is based on data from the Phase III clinical trial, PALOMA-3, in which Ibrance delayed disease progression by 6.6 months.

Government health commitments just a ‘pipedream’
The plans were “ambitions”, and primary care is not being given the time, support and funding it needs.

Vitrakvi deemed ‘not cost-effective’ by NICE
The organisation, however, encourages further data collection on similar “game changing” histology independent cancer drugs.

Sepsis death rates ‘double’ previous figures
The new study included data from low- and middle-income countries, bringing the estimated total from 5.3 million deaths to 11 million.

Janssen submits Spravato expansion in EU
The J&J division seeks to expand the use to adults with major depressive disorder who have current suicidal ideation with intent.

A&E to scrap waiting targets?
The suggestion comes after December showed the “worst waiting times on record."

NICE ‘OK’ for Lynparza
In a trial the drug stalled cancer growth for around 13.6 months compared to placebo.

Scientists discover ‘skin cancer suppressor’
Although it’s early stages, the research could eventually help develop new ways to combat melanoma.

UK cell and gene clinical trials up 45% from 2018
The industry currently supports over 3,000 jobs, with 1,700 roles in manufacturing and bioprocessing.

NICE rejects Keytruda, asks for more info
The decision, which is for HNSCC, brings the UK "further out of step with clinical practice in the rest of the world."

Could gut bacteria guard against Parkinson’s?
The results are the latest in a number of recent studies which have found a link between brain function and the digestive system.

Cyber attacks hit more than half of healthcare orgs in last year
Despite the vulnerability to cyber attacks, just 24% of companies have an adequate level of budget allocated to cyber security.

PTC submits MAA for new gene therapy
The company expects a CHMP decision in the second half of 2020.

Horizon enlists Mammoth in CRISPR move
The San Fransisco-based biotech built the first CRISPR-based detection platform for diagnostics.

Genomics England, Illumina join forces on whole genome sequencing
The partnership comes off the back of the success of the 100,000 Genomes Project in December 2018.

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CPhl worldwide

Thame Laboratories will network among the industry’s key players

Every sector of the pharmaceutical market is represented under one roof, this year in Madrid. Attending CPhI Worldwide is the most cost effective way to establish new business relationships, meet with global partners and stay updated on the latest industry trends.

Find out more: https://www.cphi.com/europe/

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